p53 gene

p53 gene·相關網站分享資訊

  • p53 - 维基百科，自由的百科全书

    zh.wikipedia.org

    活化的p53蛋白能接合於DNA，促使多個基因表現，包括基因WAF1/CIP1，其為p21蛋白之編碼基因。 p21 (WAF1)接合於G1-S/CDK (CDK2) 和S/CDK複合體(此蛋白在G1/S細胞週期節律點上有重要功能) 以抑制該複合體的活性。 當p21蛋白(WAF1) 與CDK2形成複合體時，細胞將無法進入到細胞分裂的階段。 而突變後的p53蛋白將可能 ...

  • p53 - Wikipedia

    en.wikipedia.org

    Activated p53 binds DNA and activates expression of several genes including microRNA miR-34a, WAF1/CIP1 encoding for p21 and hundreds of other down-stream genes. p21 (WAF1) binds to the G1-S/CDK (CDK4/CDK6, CDK2, and CDK1) complexes (molecules ...

  • p53 - Wikipedia

    it.wikipedia.org

    La P53, anche conosciuta come proteina tumorale 53 (gene TP53), è un fattore di trascrizione che regola il ciclo cellulare e ricopre la funzione di soppressore tumorale. La sua funzione è particolarmente importante negli organismi pluricellulari per soppr

  • Primary information of p53 gene - Home - Bioinformatics.org

    www.bioinformatics.org

    p53, also known as TP53 or tumor protein (EC :2.7.1.37) is a gene that codes for a protein that regulates the cell cycle and hence functions as a tumor suppression. It is very important for cells in multicellular organisms to suppress cancer. P53 has been

  • The p53 tumor suppressor protein - Genes and Disease - NCBI ... - NIH

    www.ncbi.nlm.nih.gov

    The p53 gene like the Rb gene, is a tumor suppressor gene, i.e., its activity stops the formation of tumors. If a person inherits only one functional copy of the p53 ...

  • TP53 tumor protein p53 [ (human)] - NCBI - NIH

    www.ncbi.nlm.nih.gov

    3 天前 - Knockdown of p53 protein promotes gliomagenesis not by altering cell growth but by arresting differentiation of Neural Stem Cells, which ...

  • The Origins and Evolution of the p53 Family of Genes - NCBI - NIH

    www.ncbi.nlm.nih.gov

    A common ancestor to the three p53 family members of human genes p53, p63, and p73 is first detected in the evolution of modern‐day sea anemones, in which ...

  • p53 : The Most Frequently Altered Gene in Human Cancers - Nature

    www.nature.com

    In contrast, the existence of tumor suppressor genes was entirely conjectural, and barely on the radar of most cancer researchers. The p53 protein was bound to ...

  • TP53 gene - Genetics Home Reference - NIH

    ghr.nlm.nih.gov

    The TP53 gene provides instructions for making a protein called tumor protein p53 (or p53). This protein acts as a tumor suppressor, which means that it ...

  • TP53 Gene - GeneCards | P53 Protein | P53 Antibody

    www.genecards.org

    Complete information for TP53 gene (Protein Coding), Tumor Protein P53, including: function, proteins, disorders, pathways, orthologs, and expression.